Webinar Recap:
Sleep and Parkinson’s Disease

Thursday | October 22, 2020
2:00 PM CST

Presented by
Dr. Amy Amara, MD, PhD

Thank you to everyone that attended the latest installment of the 2020 PAA Webinar Series, Sleep and Parkinson’s Disease, hosted by Dr. Amy Amara, MD, PhD and sponsored by Acadia Pharmaceuticals.

Sleep disturbances are common among persons with Parkinson’s Disease. This webinar explored the various sleep disorders and dysfunction that affect persons with PD as well as potential treatments and current research.

Acadia is an industry leader in the development of therapies for central nervous system disorders. We are thrilled to have their sponsorship support for this webinar along with the December and January events!

Video

Webinar Q&A

What research is encouraging for current PD patients to get more deep restful sleep?

This is covered in depth during the webinar. In sum, exercise is very important and there are several medications that have been studied that can be helpful. As always, consult your physician for any treatments reviewed during the webinar.

Can you comment on the association between circadian disruption and PD pathogenesis?

There has been some recent work on this. There was a fairly recent study utilizing a large group of people that did not have PD and who were monitored over time. It was determined that individuals with abnormal circadian rhythms were more likely to develop PD symptoms. This is a promising research area that requires additional study.

I have Parkinson’s and take 150 mg Trazodone and 40 mg Melatonin every night and still only get about 4 hours of sleep. And suggestions?

Many things to consider, including other medications you may be taking that impact sleep. Has the Trazodone and Melatonin helpful? It might be worth it to try tapering off of them slowly to see if sleep worsens or improves. Again, exercise is critical. Medication timing is also important and something you may want to discuss with your physician. For example, you may be taking alerting medications too close to bed time. Sleep hygiene and habits are also important. A sleep study may help identify recurring issues that remain unresolved, even after examining medications, medications timing and exercise. As always, consult your physician.

I am experiencing very vivid dreams and act them out. Can anything be done for this?

The is covered extensively in the presentation and video under the REM Sleep Disorder section. Melatonin and / or Clonazepam may be helpful in reducing dream enactment behavior. Sleeping in a safe space, separate of spouse or care partner may be advisable temporarily. You may need a sleep study to determine if this is truly REM Sleep Disorder behavior. For example, you may have sleep apnea which can cause sleep fragmentation and exacerbate dream enactment behavior. Again, speak with your doctor before exploring any of these medications or treatments.

Presentation

 

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