People who have higher levels of vitamin B12 in their blood when they’re diagnosed with Parkinson’s disease may be less likely to develop dementia, a study suggests. The study, “Higher vitamin B12 level at Parkinson’s disease diagnosis is associated with lower risk of future dementia,” was published in Parkinsonism & Related Disorders. Dementia describes a group […]
While there’s no evidence that people with Parkinson’s disease are more susceptible to contracting illness, COVID-19 tends to be more severe in the elderly and those with chronic diseases. Because of this, patients should take extra precautions to avoid contracting the disease, experts say. In response to the COVID-19 pandemic, the Parkinson’s Foundation (PF) recently presented a […]
Delivering a gene therapy directly to the substantia nigra, an area of the brain affected by Parkinson’s disease, led to sustained protein production for up to eight years, a post-mortem of analysis of two patients revealed. The therapy’s use failed to show significant benefits in its clinical trials, but these evaluations — covering the longest number […]
Treatment with IRLAB Therapeutics‘ small molecule IRL752 is safe and well-tolerated by Parkinson’s disease patients with dementia, and may help manage symptoms that are unresponsive to levodopa, results from a Phase 2a trial show. In particular, the treatment was found to reduce apathy, improve balance, and decrease the risk of falls. Planning and executive function also […]
If you’re in the same boat as my dad, chances are that your gym is on lockdown. Dad was disappointed to hear that Rock Steady Boxing (RSB) is pausing operations during the global coronavirus pandemic. But he also recognized that it’s the safest move. This global quarantine is really shaking up our routines, which can […]
The Goalkeeper Game, a video game in which people assume the role of a goalkeeper in a soccer penalty shootout, may be a novel tool to detect early decline in gait performance in Parkinson’s disease patients, helping them receive treatment sooner, a study suggests. The test is designed to non-invasively assess the gait of Parkinson’s […]
Today’s news is yesterday’s news, and I am sick of yesterday’s news. I am more disturbed by the news now than I was five minutes ago. Let me clarify. This news — specifically about the coronavirus — didn’t affect me as much before. I have been living in a bubble, and my bubble just burst. […]
A clinical study will test the potential of a specific magnetic resonance imaging (MRI) technique to diagnose Parkinson’s disease at early stages. The 18-month project, supported by a grant from the Center for Clinical and Translational Science in the U.K., will take place at the University of Kentucky’s College of Medicine under the leadership of […]
My chronic disease has forced me to stay home for a week after an exhausting recent trip to St. Louis. When my symptoms force me to curtail engagement outside the home, I become a “shut-in.” Many are entering voluntary home confinement due to COVID-19. People also are experiencing mandatory lockdowns by decree in several states. […]
A variant of the apolipoprotein (APOE) protein, called APOE4, has been shown to directly affect Lewy body dementias, such as Parkinson’s disease. Two separate studies, published simultaneously, found that APOE4 directly regulates levels of alpha-synuclein, which clumps to form the nerve-damaging Lewy bodies that are the main culprits of the nerve cell death that defines […]
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